A Calcium-Dependent Feedback Mechanism Participates in Shaping Single NMDA Miniature EPSCs
نویسندگان
چکیده
منابع مشابه
A calcium-dependent feedback mechanism participates in shaping single NMDA miniature EPSCs.
NMDA receptors (NMDARs) are highly calcium-permeable and are negatively regulated by intracellular calcium during prolonged exposure to agonist. We have investigated whether calcium-mediated feedback occurs during transient exposure to glutamate during single synaptic events. Examination of miniature EPSCs (mEPSCs) indicated that the decay kinetics of the NMDAR component was markedly slowed by ...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2001
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.21-01-00001.2001